WT: mesor 5.02; amplitude 0.853 (95% CI 0.674 to 1.033); peak at ZT 10.1 (95% CI 9.3 to 10.9); zero-amplitude F(2, 33) = 46.7, p = 2.4e-10
KO: mesor 4.93; amplitude 0.530 (95% CI 0.390 to 0.671); peak at ZT 13.0 (95% CI 12.0 to 14.0); zero-amplitude F(2, 33) = 29.5, p = 4.4e-08
Rhythm differs between genotypes (KO x cos and KO x sin terms): F(2, 66) = 13.58, p = 1.1e-05
Amplitude, KO - WT: -0.323 (95% CI -0.547 to -0.099)
Peak time, KO - WT: 2.8 h (95% CI 1.5 to 4.2)
For comparison, separate t-tests at each of 12 time points: p < 0.05 at ZT 8, 12, 16, 28, 36
With a Bonferroni correction for 12 tests (p < 0.05/12): ZT 16