Freezing, wild-type: tone 1 66.0%, tone 20 19.7%; knockout: tone 1 64.3%, tone 20 18.3%
A. A t-test at each of the 20 tones: 0 with p < 0.05 (tones: none); smallest p = 0.3
B. All tones pooled, tones as n (200 vs 200), t-test: knockout - wild-type -2.0 points, p = 0.43
C. Mean freezing per mouse (10 vs 10), Welch t-test: knockout - wild-type -2.0 points (95% CI -19.9 to 15.9), p = 0.82
D. Extinction slope per mouse (points per tone), Welch t-test: wild-type -2.40, knockout -2.28, difference 0.12 (95% CI -0.81 to 1.05), p = 0.79
E. Repeated-measures ANOVA, genotype x tone: F(19, 342) = 0.80, p = 0.71; Greenhouse-Geisser epsilon 0.36, corrected p = 0.59