SciGround Foundations

SciGround Math

Add automated verification to your AI. A mathematical foundation for guarantees and checks across study design, data preparation, statistical analysis, and claims.

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Mathematical verification.Across the whole chain.

  1. Design
  2. CorrespondenceThe data match the design.
  3. Data
  4. Numerical accuracyResults hold within a stated error bound.
  5. Analysis
  6. Claim followsThe conclusion is derived from the results.
  7. Claim

Verified across the chain — under the stated assumptions.

See an example

Held at every stage

Comparison
Treatment − Control
Outcome
Day-14 body weight, g
Unit
Animal, 10 per group
Groups
Assigned as designed

Declared assumptions

  • Animals are independent.
  • Outcomes are approximately normal within groups.
  • Equal variances are not required (Welch).

Mathematics changeshow you research with AI.

  • Less rechecking.More confidence.

    Automated checks make the covered calculations and conditions explicit—so less has to be checked again by hand.

  • Conclusions groundedin evidence.

    Trace each supported claim to its assumptions, mathematical basis and recorded execution.

  • Independentlyverifiable.

    Share the inputs, methods and verification records others need to inspect and reproduce the checks.

How it works.

  1. Why does the guaranteehold across stages?

    Each stage must preserve what the next stage needs. Composition theorems—results proving that guarantees from separate steps still hold when the steps are chained—connect these local guarantees to a supported final claim.

  2. Can preprocessingchange the inference?

    Preprocessing can change what a test means. The mathematical contract identifies which transformations preserve the properties needed for valid inference.

  3. Could roundingchange the decision?

    Carry numerical uncertainty through the calculation. Resolve a decision only when every value within the certified bound supports it.

  4. How is chanceaccounted for?

    Compare the observed result with the declared reference law: the range of results chance alone would produce under the study’s design. Calibration gives the evidence a mathematical meaning.

  5. How are falsediscoveries controlled?

    Testing many hypotheses needs a rule for the whole discovery list. Valid e-values (evidence scores that average at most 1 when there is no effect) and e-BH (the Benjamini–Hochberg procedure applied to them) provide an upper bound on the expected false-discovery proportion.

The mathematics.
Put to the test.

18,473

exclusion cases, every one checked

Robust to every exclusion.

In a two-group count model, removing any set of up to three of 48 observations leaves the direction of the estimated effect unchanged—proved for every case and confirmed by a separate checker.

15,285

hypotheses at genome scale

Built for genome scale.

Certified discoveries across 15,285 hypotheses in semi-synthetic genome-scale count data. Exact reference laws for every gene compute in 9 seconds for a 12 + 12 design.

+55%

true discoveries at the same error bound

More discoveries. Same guarantee.

Protected scoring raised average true discoveries from 4.08 to 6.34 across 99 held-out conditions, and the chance of at least one true discovery rose too—with the false discovery rate within the declared bound (common-U e-BH).

162,323

DESeq2 values rigorously enclosed

Real DESeq2, rigorously bounded.

Normalisation and initial dispersion values from actual DESeq2 1.42.0 runs on public RNA-seq data, enclosed in rigorous bounds across five analyses.

10 / 10

known PFOA-responsive genes recovered

Known biology, recovered.

On public rat liver toxicology data, the verification rule recovered all ten known PFOA-responsive genes at 2.5 mg/kg and above.

98 / 98

verifier tests passed

Checked outside the producer.

An independently implemented verifier recomputes the covered checks with exact rational arithmetic and passes every test in its suite.

Depth beneath the results.

  • Certificate size

    Fewer states to certify.

    Exclusions that lead to the same analysis are merged: 697 states become 487 and the certificate shrinks by 29.6%.

  • Optimality

    The optimum, proved.

    For fixed discovery tables, the exact best achievable result is derived—and reached.

  • Method choice

    Exact conditions for simpler scores.

    Necessary and sufficient conditions show when a simpler ordered score can replace a four-tier score without losing discoveries.

  • Preprocessing

    Shared rescaling keeps the guarantee.

    Centring and scaling learned from the data and applied to both groups leave the test and its guarantee exactly intact.

  • Interval certification

    Whole regions, not points.

    Interval arithmetic certifies entire regions of continuous parameters, not just sampled values.

  • Design

    Feasibility before data.

    From the design alone, compute the minimum number of discoveries certification can reach—before collecting a sample.

Read the scoped validation summaries

Connect the analysis.
Keep the guarantee.

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